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Itaconate charges down inflammation

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The metabolite itaconate induces electrophilic stress that induces an antioxidant response and regulates secondary TLR transcriptional responses and IL-17-driven pathology. Click to show full abstract

The metabolite itaconate induces electrophilic stress that induces an antioxidant response and regulates secondary TLR transcriptional responses and IL-17-driven pathology.

Keywords: charges inflammation; itaconate; itaconate charges; immunology

Journal Title: Nature Reviews Immunology
Year Published: 2018

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