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Trans-Golgi network breaks away to activate NLRP3

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NLRP3 activators cause disassembly of the trans-Golgi network, and the dispersed trans-Golgi network serves as a scaffold for NLRP3 inflammasome assembly and activation. Click to show full abstract

NLRP3 activators cause disassembly of the trans-Golgi network, and the dispersed trans-Golgi network serves as a scaffold for NLRP3 inflammasome assembly and activation.

Keywords: away activate; network breaks; golgi network; trans golgi; breaks away

Journal Title: Nature Reviews Immunology
Year Published: 2019

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