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Many eukaryotic proteins, including key transcription regulators, contain intrinsically disordered regions (IDRs), which serve as flexible interaction platforms. The molecular understanding of IDR-based interactions is now emerging, providing new insights… Click to show full abstract
Many eukaryotic proteins, including key transcription regulators, contain intrinsically disordered regions (IDRs), which serve as flexible interaction platforms. The molecular understanding of IDR-based interactions is now emerging, providing new insights into how IDRs promote protein compartmentalization and/or phase separation and how these processes regulate gene expression.
Keywords:
intrinsic disorder;
biology;
concentrating intrinsic
Journal Title: Nature Reviews Molecular Cell Biology
Year Published: 2018
Link to full text (if available)
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Journal Title: Nature Reviews Molecular Cell Biology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!