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Transcriptionally tailored break repair

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DNA double-strand breaks at active genes are repaired by a dedicated homologous recombination mechanism involving R-loop formation and RAD52 recruitment. Click to show full abstract

DNA double-strand breaks at active genes are repaired by a dedicated homologous recombination mechanism involving R-loop formation and RAD52 recruitment.

Keywords: transcriptionally tailored; break repair; biology; tailored break

Journal Title: Nature Reviews Molecular Cell Biology
Year Published: 2018

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