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Extracellular serine feeds cancer skin stem cells

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Premalignant skin stem cells become dependent on extracellular serine for proliferation, and this metabolic reprogramming inhibits tumour-suppressing cell differentiation. Click to show full abstract

Premalignant skin stem cells become dependent on extracellular serine for proliferation, and this metabolic reprogramming inhibits tumour-suppressing cell differentiation.

Keywords: skin stem; stem cells; serine feeds; extracellular serine

Journal Title: Nature Reviews Molecular Cell Biology
Year Published: 2020

Link to full text (if available)


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