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Modelling diabetic vasculopathy with human vessel organoids

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A new study reports that human blood vessel organoids can be generated through the directed differentiation of human pluripotent stem cells. Use of these blood vessel organoids to model diabetic… Click to show full abstract

A new study reports that human blood vessel organoids can be generated through the directed differentiation of human pluripotent stem cells. Use of these blood vessel organoids to model diabetic vasculopathy led to the identification of a new potential therapeutic target, suggesting that this system could have translational value for studies of diabetes complications.

Keywords: human vessel; modelling diabetic; diabetic vasculopathy; vessel organoids; vessel; vasculopathy human

Journal Title: Nature Reviews Nephrology
Year Published: 2019

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