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A recent study reports the first high-resolution, cryo-electron microscopy-based structure of zebrafish Na+-K+-Cl− cotransporter 1 (NKCC1). This structure provides important insights into the determinants of ion translocation by NKCC1 and… Click to show full abstract
A recent study reports the first high-resolution, cryo-electron microscopy-based structure of zebrafish Na+-K+-Cl− cotransporter 1 (NKCC1). This structure provides important insights into the determinants of ion translocation by NKCC1 and other cation-Cl− cotransporters such as NKCC2. It could thus facilitate the design of drugs to target these transporters individually.
Keywords:
nephrology;
microscopy;
structure cotransporter;
cotransporter;
structure
Journal Title: Nature Reviews Nephrology
Year Published: 2019
Link to full text (if available)
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Journal Title: Nature Reviews Nephrology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!