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Testing the anti-osteoclastic function of biologic DMARDs

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A variety of biologic DMARDs now exist for the treatment of rheumatoid arthritis, but we don’t really know how these drugs function in vivo. Can time-lapse intravital imaging distinguish the… Click to show full abstract

A variety of biologic DMARDs now exist for the treatment of rheumatoid arthritis, but we don’t really know how these drugs function in vivo. Can time-lapse intravital imaging distinguish the modes of action of DMARDs by comparing response to joint destruction in mouse models of arthritis?

Keywords: biologic dmards; biologic; testing anti; osteoclastic function; function biologic; anti osteoclastic

Journal Title: Nature Reviews Rheumatology
Year Published: 2018

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