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HLA autoimmunity risk alleles influence T cell receptor sequences

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New research demonstrates that the amino acid composition of the hypervariable CDR3 region of T cell receptors is influenced by the presence of HLA risk alleles for autoimmune disease. Click to show full abstract

New research demonstrates that the amino acid composition of the hypervariable CDR3 region of T cell receptors is influenced by the presence of HLA risk alleles for autoimmune disease.

Keywords: risk alleles; autoimmunity risk; cell; alleles influence; hla autoimmunity

Journal Title: Nature Reviews Rheumatology
Year Published: 2022

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