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Priority index for human genetics and drug discovery.

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Although human genetics can help identify new drug targets, the best way to prioritize genes as therapeutic targets is uncertain. A new study describes a framework to prioritize potential targets… Click to show full abstract

Although human genetics can help identify new drug targets, the best way to prioritize genes as therapeutic targets is uncertain. A new study describes a framework to prioritize potential targets by integrating genome-wide association data with genomic features, disease ontologies and network connectivity.

Keywords: index human; genetics drug; genetics; human genetics; priority index

Journal Title: Nature Genetics
Year Published: 2019

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