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Metabolic engineering offers the flexibility to meet market demand for bioactive natural products but can be hampered when a necessary protein or intermediate is toxic. In yeast, modifying the subcellular… Click to show full abstract
Metabolic engineering offers the flexibility to meet market demand for bioactive natural products but can be hampered when a necessary protein or intermediate is toxic. In yeast, modifying the subcellular localization of biosynthetic enzymes can alleviate toxicity and increase production titer.
Keywords:
synthetic yeast;
brews neuroactive;
neuroactive compounds;
yeast brews;
biology
Journal Title: Nature Chemical Biology
Year Published: 2020
Link to full text (if available)
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Journal Title: Nature Chemical Biology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!