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Drivers of intrinsic resistance

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Precision oncology requires an understanding of the genes and pathways that dictate therapeutic response. Through specialized analysis of drug sensitivity patterns across hundreds of genomically annotated cancer cell lines, specific… Click to show full abstract

Precision oncology requires an understanding of the genes and pathways that dictate therapeutic response. Through specialized analysis of drug sensitivity patterns across hundreds of genomically annotated cancer cell lines, specific and actionable drivers of intrinsic resistance have been identified.

Keywords: oncology; biology; drivers intrinsic; intrinsic resistance

Journal Title: Nature Chemical Biology
Year Published: 2022

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