Photo from wikipedia
The righting reflex (RR) is frequently used to assess level of arousal and applied to animal models of a range of neurological disorders. RR produces a binary result that, when… Click to show full abstract
The righting reflex (RR) is frequently used to assess level of arousal and applied to animal models of a range of neurological disorders. RR produces a binary result that, when positive, is used to infer restoration of consciousness, often without further behavioral corroboration. We find that RR is an unreliable metric for arousal/recovery of consciousness. Instead, cortical activity and motor behavior that accompany RR are a non-binary, superior criterion that accurately calibrates and establishes level of arousal in rodents.
Keywords:
alternative righting;
robust alternative;
righting reflex;
reflex assess;
arousal rodents;
arousal
Journal Title: Scientific Reports
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Scientific Reports
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!