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Know Your Model: Why mouse inbred strain contribution matters

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Strain contributions arising from the strain of origin and backcrosses can modify phenotypic severity and/or penetrance of mutant alleles in mouse models. Click to show full abstract

Strain contributions arising from the strain of origin and backcrosses can modify phenotypic severity and/or penetrance of mutant alleles in mouse models.

Keywords: inbred strain; strain contribution; mouse inbred; model mouse; know model; contribution matters

Journal Title: Lab Animal
Year Published: 2020

Link to full text (if available)


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