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Extracellular protein degradation via the lysosome

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Tight regulation of protein levels is so crucial for cellular function that mammalian cells have evolved two parallel degradation systems. This article discusses how these systems can be exploited to… Click to show full abstract

Tight regulation of protein levels is so crucial for cellular function that mammalian cells have evolved two parallel degradation systems. This article discusses how these systems can be exploited to selectively target proteins of interest for therapeutic purposes.

Keywords: protein; degradation; via lysosome; extracellular protein; protein degradation; degradation via

Journal Title: Communications Chemistry
Year Published: 2020

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