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Microfluidic biochip and integrated diffractive optics for bacteria growth control and monitoring

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We present a simple and inexpensive method for enabling bacterial cell capture in a 2D array of traps, such that their growth can be monitored under controlled dynamic environments through… Click to show full abstract

We present a simple and inexpensive method for enabling bacterial cell capture in a 2D array of traps, such that their growth can be monitored under controlled dynamic environments through diffractive optics integrated into a microfluidic chip. As an example, we demonstrate the feasibility for E. coli capture and expansion within the monolayer trap; the resulting increase in the diffraction signal is consistent with the cells' exponential growth rate.

Keywords: biochip integrated; optics; diffractive optics; growth; integrated diffractive; microfluidic biochip

Journal Title: Analytical Methods
Year Published: 2017

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