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Real-time analysis of Pd2(dba)3 activation by phosphine ligands.

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A combination of UV-Vis spectroscopy and electrospray ionization mass spectrometry is used for real-time monitoring of Pd2(dba)3 activation with sulfonated versions of PPh3 and Buchwald-type ligands. This provides insight into… Click to show full abstract

A combination of UV-Vis spectroscopy and electrospray ionization mass spectrometry is used for real-time monitoring of Pd2(dba)3 activation with sulfonated versions of PPh3 and Buchwald-type ligands. This provides insight into the effect of ligand and preparation conditions on activation and allows for establishment of rational activation protocols.

Keywords: real time; time analysis; pd2 dba; activation; dba activation

Journal Title: Chemical communications
Year Published: 2017

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