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Turn-on fluorescence detection of pyrophosphate anion based on DNA-attached cobalt oxyhydroxide

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The turn-on fluorescence of pyrophosphate anion (PPi) was detected using DNA-attached cobalt oxyhydroxide. The fluorescence signal was quenched when carboxyfluorescein-labeled ssDNA was adsorbed by CoOOH nanoflakes through electrostatic interaction. With… Click to show full abstract

The turn-on fluorescence of pyrophosphate anion (PPi) was detected using DNA-attached cobalt oxyhydroxide. The fluorescence signal was quenched when carboxyfluorescein-labeled ssDNA was adsorbed by CoOOH nanoflakes through electrostatic interaction. With the addition of target PPi, PPi competed with DNA for CoOOH nanoflakes, resulting in turn-on fluorescence.

Keywords: attached cobalt; cobalt oxyhydroxide; dna attached; turn fluorescence; pyrophosphate anion

Journal Title: New Journal of Chemistry
Year Published: 2017

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