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Inducible epitope imprinting: 'generating' the required binding site in membrane receptors for targeted drug delivery.

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We report an inducible epitope imprinting strategy that as a template, a flexible peptide chain can have a disordered-to-ordered conformational change by suitable inducement through a molecular imprinting procedure, and… Click to show full abstract

We report an inducible epitope imprinting strategy that as a template, a flexible peptide chain can have a disordered-to-ordered conformational change by suitable inducement through a molecular imprinting procedure, and the formed nanoparticles can, in turn, remold the original peptide into the expected conformation and specifically bind to the corresponding protein.

Keywords: required binding; generating required; epitope imprinting; inducible epitope; imprinting generating

Journal Title: Nanoscale
Year Published: 2017

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