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One step construction of a taxane-like skeleton by a diendiyne metathesis cyclization reaction

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One-step cyclization for the formation of the characteristic tricyclic system of taxanes is described. This process is based on a cascade metathesis cyclization reaction that allows the preparation of novel… Click to show full abstract

One-step cyclization for the formation of the characteristic tricyclic system of taxanes is described. This process is based on a cascade metathesis cyclization reaction that allows the preparation of novel taxane derivatives in a fast and simple manner.

Keywords: metathesis cyclization; cyclization; one step; cyclization reaction

Journal Title: Organic chemistry frontiers
Year Published: 2017

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