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An efficient asymmetric cyclization reaction of amino-acid-derived isothiocyanates with azodicarboxylates is described. The chiral 1,2,4-triazolines are prepared in good yield (up to 87%) and enantioselectivities (up to 95% ee). Click to show full abstract
An efficient asymmetric cyclization reaction of amino-acid-derived isothiocyanates with azodicarboxylates is described. The chiral 1,2,4-triazolines are prepared in good yield (up to 87%) and enantioselectivities (up to 95% ee).
Keywords:
containing chiral;
synthesis enantioenriched;
enantioenriched triazolines;
triazolines containing;
organocatalytic synthesis;
chiral quaternary
Journal Title: RSC Advances
Year Published: 2017
Link to full text (if available)
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Journal Title: RSC Advances
Year Published: 2017
Link to full text (if available)
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recommendations!