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Nontoxic organic solvents identified using an a priori approach with Hansen solubility parameters.

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Nontoxicities of organic solvents were predicted using Hansen solubility parameters and various truly nontoxic solvents were identified according to the prediction. The nontoxicity of solvents originates from their exhibition of… Click to show full abstract

Nontoxicities of organic solvents were predicted using Hansen solubility parameters and various truly nontoxic solvents were identified according to the prediction. The nontoxicity of solvents originates from their exhibition of poor solubility or low diffusivity toward cell constituents and good stability against hydrolytic degradation.

Keywords: organic solvents; nontoxic organic; solvents identified; hansen solubility; solubility; solubility parameters

Journal Title: Chemical communications
Year Published: 2017

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