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The recognition mechanism of triple-helical β-1,3-glucan by a β-1,3-glucanase.

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β-1,3-Glucan is one of the most abundant polysaccharides in fungi. Recognition of β-1,3-glucan occurs in both hydrolysis by glycoside hydrolases and immunological recognition. Our study provides a novel structural account… Click to show full abstract

β-1,3-Glucan is one of the most abundant polysaccharides in fungi. Recognition of β-1,3-glucan occurs in both hydrolysis by glycoside hydrolases and immunological recognition. Our study provides a novel structural account of how glycoside hydrolase recognizes and hydrolyzes substrates in a triple-helical form and presents a general structural basis of β-1,3-glucan recognition.

Keywords: helical glucan; recognition mechanism; recognition; glucan glucanase; triple helical; mechanism triple

Journal Title: Chemical communications
Year Published: 2017

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