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A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells.

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Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a… Click to show full abstract

Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a cell membrane-anchored sensor for the detection of cytokines secreted by single cells using a combination of aptamer-based sensors and droplet microfluidics.

Keywords: aptamer sensor; anchored aptamer; secretion; single cells; membrane anchored

Journal Title: Chemical communications
Year Published: 2017

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