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Sequential molecule-triggered-release system based on acetylated amylose helix aggregates.

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We developed a novel sequential molecule-triggered-release system based on acetylated amylose helix aggregates with a proper degree of substitution, in which a loaded molecule can be trigger-released by trigger molecules… Click to show full abstract

We developed a novel sequential molecule-triggered-release system based on acetylated amylose helix aggregates with a proper degree of substitution, in which a loaded molecule can be trigger-released by trigger molecules in sequence. The system is sensitive and capable of time-controllable triggered release. The mechanism involves the sequential pushing of wrapped molecules with low binding free energy out of the helix cavity by a triggered molecule with a high binding free energy.

Keywords: molecule; system; sequential molecule; helix; triggered release

Journal Title: Chemical communications
Year Published: 2017

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