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DNA-crowded enzyme complexes with enhanced activities and stabilities.

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We present a robust and simple method to prepare DNA-crowded enzyme complexes by directly assembling long DNA duplexes on the enzyme surface. DNA-crowded enzyme complexes show boosted substrate turnover numbers,… Click to show full abstract

We present a robust and simple method to prepare DNA-crowded enzyme complexes by directly assembling long DNA duplexes on the enzyme surface. DNA-crowded enzyme complexes show boosted substrate turnover numbers, and increased stabilities against various storage conditions. They could be potentially scaled up for applications in biomaterials and biotechnology.

Keywords: complexes enhanced; dna crowded; enzyme complexes; crowded enzyme

Journal Title: Chemical communications
Year Published: 2017

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