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A highly efficient nickel catalysed method for the direct C2-arylation of N-heterocyclic carbenes (NHCs) is reported. This protocol enables a facile access to C2-arylated imidazolium salts (NHC-Ar)X (X = Cl,… Click to show full abstract
A highly efficient nickel catalysed method for the direct C2-arylation of N-heterocyclic carbenes (NHCs) is reported. This protocol enables a facile access to C2-arylated imidazolium salts (NHC-Ar)X (X = Cl, Br, I or OTf). Experimental and theoretical studies suggest the viability of a Ni(i)/Ni(ii) catalytic pathway in which the dinuclear Ni(i) species [(NHC)NiX]2 plays a key role.
Keywords:
direct arylation;
nickel catalysed;
heterocyclic carbenes;
arylation heterocyclic
Journal Title: Dalton transactions
Year Published: 2017
Link to full text (if available)
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Journal Title: Dalton transactions
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!