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An atom-economical protocol for direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes in water

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This paper describes an atom-economical strategy for the direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes under metal free conditions with excellent functional group tolerance. The use of stable-nontoxic Oxone… Click to show full abstract

This paper describes an atom-economical strategy for the direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes under metal free conditions with excellent functional group tolerance. The use of stable-nontoxic Oxone as a terminal oxidant along with an inexpensive salt (sodium chloride) as a halogen source and water as the reaction medium makes this chemical synthetic process more viable and environmentally benign contributing towards green chemistry.

Keywords: hillman alcohols; baylis hillman; chemistry; conversion baylis; direct conversion; atom economical

Journal Title: Green Chemistry
Year Published: 2017

Link to full text (if available)


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