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MicroRNA detection at femtomolar concentrations with isothermal amplification and a biological nanopore.

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One of the greatest challenges faced by chemists and biologists is the detection of molecules at extremely low concentrations. This paper describes a method to detect ultra-low concentrations (1 femtomole)… Click to show full abstract

One of the greatest challenges faced by chemists and biologists is the detection of molecules at extremely low concentrations. This paper describes a method to detect ultra-low concentrations (1 femtomole) of nucleotides using isothermal amplification and a biological nanopore.

Keywords: amplification biological; biological nanopore; isothermal amplification; detection femtomolar; microrna detection

Journal Title: Nanoscale
Year Published: 2017

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