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Post-targeting strategy for ready-to-use targeted nanodelivery post cargo loading.

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Based on boronate formation, this study reports a post-targeting methodology capable of readily installing versatile targeting modules onto a cargo-loaded nanoplatform in aqueous mediums. This permits the targeted nanodelivery of… Click to show full abstract

Based on boronate formation, this study reports a post-targeting methodology capable of readily installing versatile targeting modules onto a cargo-loaded nanoplatform in aqueous mediums. This permits the targeted nanodelivery of broad-spectrum therapeutics (drug/gene) in a ready-to-use manner while overcoming the PEGylation-dilemma that frequently occurs in conventional targeting approaches.

Keywords: ready use; post targeting; post; targeted nanodelivery; cargo

Journal Title: Nanoscale
Year Published: 2017

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