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Lysozyme-catalyzed formation of a conjugated polyacetylene

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Hen egg white lysozyme catalyzes the polymerization of 2-ethynylpyridine in water as the singular protein catalyst. Inhibition and NMR spectroscopy studies support the hypothesis that polymerization takes place in the… Click to show full abstract

Hen egg white lysozyme catalyzes the polymerization of 2-ethynylpyridine in water as the singular protein catalyst. Inhibition and NMR spectroscopy studies support the hypothesis that polymerization takes place in the active site cleft of the protein. This discovery marks the first time a metal-free hydrolase has been observed activating the formation for a conjugated polymer.

Keywords: conjugated polyacetylene; lysozyme catalyzed; formation; formation conjugated; spectroscopy; catalyzed formation

Journal Title: Polymer Chemistry
Year Published: 2017

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