An efficient access to amino substituted phenanthridine and isoquinoline derivatives, through palladium-catalyzed C(sp2)–H aminoimidoylation, has been developed. This process applies O-benzoyl hydroxylamines as oxidative amino sources to generate amino Pd(II)… Click to show full abstract
An efficient access to amino substituted phenanthridine and isoquinoline derivatives, through palladium-catalyzed C(sp2)–H aminoimidoylation, has been developed. This process applies O-benzoyl hydroxylamines as oxidative amino sources to generate amino Pd(II) intermediates, followed by isocyanide insertion and intramolecular C(sp2)–H activation. Sequential C–N and C–C bond formation took place on isocyano-containing arenes in one step.
Keywords:
amino;
catalyzed sp2;
palladium catalyzed;
sp2 aminoimidoylation;
amino substituted;
isocyano containing
Journal Title: Organic chemistry frontiers
Year Published: 2017
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Journal Title: Organic chemistry frontiers
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!