Photo from academic.microsoft.com
The highly efficient direct catalytic reductive amination of aromatic ketones with diphenylmethanamine is described. Catalyzed by the iridium–monodentate phosphoramidite complex and assisted using additives, this concise and practical route provided… Click to show full abstract
The highly efficient direct catalytic reductive amination of aromatic ketones with diphenylmethanamine is described. Catalyzed by the iridium–monodentate phosphoramidite complex and assisted using additives, this concise and practical route provided chiral amines in high yields and with high enantioselectivity (ee values of up to 99%).
Keywords:
amination aromatic;
aromatic ketones;
iridium catalyzed;
reductive amination;
catalyzed direct
Journal Title: Organic chemistry frontiers
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Organic chemistry frontiers
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!