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A copper-catalyzed cascade radical 1,2-cyclization of indoles with arylsulfonyl hydrazides was developed, affording a series of 2-thiolated 3H-pyrrolo[1,2-a]indoles in moderate to excellent yields. This transformation proceeded with sequential radical addition… Click to show full abstract
A copper-catalyzed cascade radical 1,2-cyclization of indoles with arylsulfonyl hydrazides was developed, affording a series of 2-thiolated 3H-pyrrolo[1,2-a]indoles in moderate to excellent yields. This transformation proceeded with sequential radical addition to a triple bond and a cyclization procedure, where arylsulfonyl hydrazides served as thioarylation reagents.
Keywords:
cyclization indoles;
indoles arylsulfonyl;
radical cyclization;
cyclization;
arylsulfonyl hydrazides;
copper catalyzed
Journal Title: Organic chemistry frontiers
Year Published: 2017
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Journal Title: Organic chemistry frontiers
Year Published: 2017
Link to full text (if available)
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recommendations!