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Pd-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups

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The Pd(II)-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups, prevalent organic motifs found in vital biological and pharmaceutical molecules, has been achieved for the first… Click to show full abstract

The Pd(II)-catalyzed C–H arylation of benzothioamides with boronic acids using thioamides as directing groups, prevalent organic motifs found in vital biological and pharmaceutical molecules, has been achieved for the first time. The reactions proceed with high functional group tolerance in yields of 21–84%.

Keywords: boronic acids; arylation benzothioamides; using thioamides; acids using; catalyzed arylation; benzothioamides boronic

Journal Title: Organic chemistry frontiers
Year Published: 2017

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