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Dirhodium(II)-catalyzed nitrene transfers have been used to prepare a novel synthetic platform bearing the triamino moiety present in pactamycin, jogyamycin and cranomycin. Catalytic intramolecular C(sp3)–H amination and alkene aziridination reactions,… Click to show full abstract
Dirhodium(II)-catalyzed nitrene transfers have been used to prepare a novel synthetic platform bearing the triamino moiety present in pactamycin, jogyamycin and cranomycin. Catalytic intramolecular C(sp3)–H amination and alkene aziridination reactions, the latter followed by a nucleophilic aziridine ring opening, are the key steps of this strategy.
Keywords:
alkene aziridination;
pactamycin;
sp3 amination
Journal Title: Organic chemistry frontiers
Year Published: 2018
Link to full text (if available)
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Journal Title: Organic chemistry frontiers
Year Published: 2018
Link to full text (if available)
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recommendations!