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Synthesis and optical properties of cyanine dyes with an aromatic azonia skeleton

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Six cyanine dyes with an aromatic azonia skeleton (1a–f) were obtained by the reaction of chlorinated heptamethylene cyanine and 2-aminopyridine derivatives. Five of them (1a–d and 1f) emit red and… Click to show full abstract

Six cyanine dyes with an aromatic azonia skeleton (1a–f) were obtained by the reaction of chlorinated heptamethylene cyanine and 2-aminopyridine derivatives. Five of them (1a–d and 1f) emit red and near-infrared fluorescence at 600–800 nm. The fluorescent stains of living cells indicate that they can penetrate the cell membrane, especially the hydroxyl-substituted dye (1c), it has lysosome targeting ability.

Keywords: dyes aromatic; azonia skeleton; aromatic azonia; optical properties; cyanine dyes; synthesis optical

Journal Title: Organic chemistry frontiers
Year Published: 2018

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