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A dansyl-based fluorescent probe for the highly selective detection of cysteine based on a d-PeT switching mechanism

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A novel fluorescent probe, DN-C, for detection of cysteine (Cys) based on a d-PeT switching mechanism is reported. In the presence of Cys, the probe exhibits a turn-on fluorescence signal… Click to show full abstract

A novel fluorescent probe, DN-C, for detection of cysteine (Cys) based on a d-PeT switching mechanism is reported. In the presence of Cys, the probe exhibits a turn-on fluorescence signal and nearly 28-fold fluorescence intensity enhancement. The cellular imaging experiment indicated the DN-C possess desirable cell permeability for biological applications.

Keywords: detection cysteine; switching mechanism; fluorescent probe; pet switching; probe; based pet

Journal Title: RSC Advances
Year Published: 2017

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