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Tri(o-tolyl)phosphine for highly efficient Suzuki coupling of propargylic carbonates with boronic acids.

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A highly efficient catalytic system consisting of Pd2(dba)3·CHCl3 and tri(o-tolyl)phosphine has been identified for the coupling of propargylic carbonates with different types of organo boronic acids at room temperature. Excellent… Click to show full abstract

A highly efficient catalytic system consisting of Pd2(dba)3·CHCl3 and tri(o-tolyl)phosphine has been identified for the coupling of propargylic carbonates with different types of organo boronic acids at room temperature. Excellent central-to-axial chirality transfer was also demonstrated.

Keywords: boronic acids; propargylic carbonates; coupling propargylic; tri tolyl; highly efficient; tolyl phosphine

Journal Title: Chemical communications
Year Published: 2018

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