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Described herein is the merging of allylic C(sp3)-H activation and directed C(sp2)-H activation into a single approach for discovering unprecedented chemical transformations. As a proof-of-concept, we disclose for the first… Click to show full abstract
Described herein is the merging of allylic C(sp3)-H activation and directed C(sp2)-H activation into a single approach for discovering unprecedented chemical transformations. As a proof-of-concept, we disclose for the first time the rhodium-catalyzed regioselective oxidative annulation of anilines with allylbenzenes to deliver a variety of indoles. In this work, the C3 and C2 positions of the allylic segment are set to construct C-N and C-C bonds, respectively.
Keywords:
oxidative annulation;
rhodium;
catalyzed regioselective;
anilines allylbenzenes;
regioselective oxidative;
annulation anilines
Journal Title: Chemical communications
Year Published: 2019
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Journal Title: Chemical communications
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!