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Solvent-assisted synthesis of a shape-persistent chiral polyaza gigantocycle characterized by a very large internal cavity and extraordinarily high amplitude of the ECD exciton couplet.

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A giant, chiral square-shaped octaimine macrocycle has been obtained in a controlled manner from readily available and inexpensive substrates: 9,10-diphenylanthracene-based dialdehyde and trans-1,2-diaminocyclohexane. Reduction of the polyimine led to a… Click to show full abstract

A giant, chiral square-shaped octaimine macrocycle has been obtained in a controlled manner from readily available and inexpensive substrates: 9,10-diphenylanthracene-based dialdehyde and trans-1,2-diaminocyclohexane. Reduction of the polyimine led to a chiral octaamine characterized by a very large internal hydrophobic cavity.

Keywords: characterized large; solvent assisted; cavity; assisted synthesis; large internal; synthesis shape

Journal Title: Chemical communications
Year Published: 2019

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