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After more than 50 years of platinum-based anticancer research only three compounds are in clinical use worldwide. The use of the well-known lead compound of this class of anticancer agents,… Click to show full abstract
After more than 50 years of platinum-based anticancer research only three compounds are in clinical use worldwide. The use of the well-known lead compound of this class of anticancer agents, cisplatin, is limited by its side effects and varying resistance mechanisms. Therefore, we report on platinum(ii) compounds with asparagusic acid derivatives as ligands which show interesting anticancer results on cisplatin resistant cell lines.
Keywords:
platinum;
characterization biological;
derivatives ligands;
acid derivatives;
asparagusic acid;
synthesis characterization
Journal Title: Dalton transactions
Year Published: 2019
Link to full text (if available)
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Journal Title: Dalton transactions
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!