The authors thank the MINECO (Severo Ochoa, CTQ2015-69153-C2-1-R, CTQ2015-69153-C2-2-R and CTQ2015-67461-P), Diputacion General de Aragon (Grupo Consolidado E21) and Universitat Jaume I (P1.1B2015-09) for financial support. P. Borja thanks the… Click to show full abstract
The authors thank the MINECO (Severo Ochoa, CTQ2015-69153-C2-1-R, CTQ2015-69153-C2-2-R and CTQ2015-67461-P), Diputacion General de Aragon (Grupo Consolidado E21) and Universitat Jaume I (P1.1B2015-09) for financial support. P. Borja thanks the Universitat Jaume I for a postdoctoral grant. The authors are very grateful to the 'Serveis Centrals d'Instrumentacio Cientifica (SCIC)' of the Universitat Jaume I, S. Fuertes (Universidad of Zaragoza) for data collection of the X-ray structure of 4 and to the Instituto de Biocomputacion y Fisica de Sistemas Complejos (BIFI) and the Centro de Supercomputacion de Galicia (CESGA) for the generous allocation of computational resources.
               
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