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A practical sulfa-Michael/aldol cascade reaction of 1,4-dithiane-2,5-diol and α-aryl-β-nitroacrylates has been developed, which allows efficient access to functionalized 2,5-dihydrothiophenes bearing a quaternary carbon stereocenter in moderate to good yields with… Click to show full abstract
A practical sulfa-Michael/aldol cascade reaction of 1,4-dithiane-2,5-diol and α-aryl-β-nitroacrylates has been developed, which allows efficient access to functionalized 2,5-dihydrothiophenes bearing a quaternary carbon stereocenter in moderate to good yields with high enantioselectivities.
Keywords:
aldol cascade;
dihydrothiophenes bearing;
sulfa michael;
functionalized dihydrothiophenes;
michael aldol;
bearing quaternary
Journal Title: RSC Advances
Year Published: 2018
Link to full text (if available)
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Journal Title: RSC Advances
Year Published: 2018
Link to full text (if available)
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recommendations!