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Site-specific labeling of an anti-MUC1 antibody: probing the effects of conjugation and linker chemistry on the internalization process

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Four antibody conjugates were prepared to investigate how the conjugation and linker chemistry would impact ADC endocytosis and intracellular trafficking. Click to show full abstract

Four antibody conjugates were prepared to investigate how the conjugation and linker chemistry would impact ADC endocytosis and intracellular trafficking.

Keywords: chemistry; conjugation linker; linker chemistry; antibody

Journal Title: RSC Advances
Year Published: 2019

Link to full text (if available)


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