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Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria† †Electronic supplementary information (ESI) available. CCDC 1831467 and 1831468. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8sc01325j

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Mining the genome to harvest from the metabolome: a well-directed search for bioactive natural products unearths the pyxidicyclines from Pyxidicoccus. Click to show full abstract

Mining the genome to harvest from the metabolome: a well-directed search for bioactive natural products unearths the pyxidicyclines from Pyxidicoccus.

Keywords: resistance guided; genome mining; uncovers new; mining uncovers; guided genome; self resistance

Journal Title: Chemical Science
Year Published: 2018

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