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Degradable polymer prodrugs with adjustable activity from drug-initiated radical ring-opening copolymerization† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02256a

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Degradable polymer prodrugs were synthesized by ‘drug-initiated’ nitroxide-mediated radical ring-opening copolymerization and led to either nanoparticles or soluble prodrugs with adjustable cytotoxicity on two different cancer cell lines. Click to show full abstract

Degradable polymer prodrugs were synthesized by ‘drug-initiated’ nitroxide-mediated radical ring-opening copolymerization and led to either nanoparticles or soluble prodrugs with adjustable cytotoxicity on two different cancer cell lines.

Keywords: drug initiated; ring opening; opening copolymerization; radical ring; polymer prodrugs; degradable polymer

Journal Title: Chemical Science
Year Published: 2018

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