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Tuning the reactivity of nitriles using Cu(ii) catalysis – potentially prebiotic activation of nucleotides† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02513d

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A synergistic system was established involving activating nucleotides with nitriles using Cu(ii) and protecting RNA degradation by byproducts of alpha-aminonitriles. Click to show full abstract

A synergistic system was established involving activating nucleotides with nitriles using Cu(ii) and protecting RNA degradation by byproducts of alpha-aminonitriles.

Keywords: potentially prebiotic; reactivity nitriles; using catalysis; tuning reactivity; nitriles using; catalysis potentially

Journal Title: Chemical Science
Year Published: 2018

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