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Oxidative steps during the biosynthesis of squalestatin S1† †Electronic supplementary information (ESI) available: All experimental procedures and analytical data. See DOI: 10.1039/c8sc02615g

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Two enzymes of previously unknown function encoded by the squalestatin biosynthetic gene cluster from the fungus Phoma MF5453 catalyse a remarkable series of six consecutive oxidations to form the 4,8-dioxa-bicyclo[3.2.1]octane… Click to show full abstract

Two enzymes of previously unknown function encoded by the squalestatin biosynthetic gene cluster from the fungus Phoma MF5453 catalyse a remarkable series of six consecutive oxidations to form the 4,8-dioxa-bicyclo[3.2.1]octane core of the squalestatins.

Keywords: steps biosynthesis; oxidative steps; supplementary information; squalestatin electronic; biosynthesis squalestatin; electronic supplementary

Journal Title: Chemical Science
Year Published: 2019

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