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The condensation domain synthesising the last peptide bond in glycopeptide antibiotic biosynthesis has a preference for linear peptide substrates, with effective peptide formation linked to the rate of amino acid… Click to show full abstract
The condensation domain synthesising the last peptide bond in glycopeptide antibiotic biosynthesis has a preference for linear peptide substrates, with effective peptide formation linked to the rate of amino acid activation by the preceding adenylation domain.
Keywords:
antibiotic biosynthesis;
condensation domain;
glycopeptide antibiotic
Journal Title: Chemical Science
Year Published: 2019
Link to full text (if available)
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Journal Title: Chemical Science
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!